abstract：OBJECTIVE:To evaluate triptan use patterns in a large Israeli HMO district. BACKGROUND:Triptans, 5HT(1B/1D) agonists, provide an effective and safe relief of headache and accompanying symptoms during an acute migraine attack. METHOD:We retrospectively reviewed the computerized prescription filling data of 1498 patien...

journal_title：Headache

authors： Ifergane G,Wirguin I,Shvartzman P

更新日期：2006-09-01 00:00:00

abstract：:The author reports the use of pregabalin in a patient with glossopharyngeal neuralgia. The patient achieved complete pain relief and tolerated the medication. This is the first published report of the use of this medicine for glossopharyngeal neuralgia. ...

journal_title：Headache

authors： Kitchener JM

更新日期：2006-09-01 00:00:00

abstract：:Biomarkers are physical signs or laboratory measurements that occur in association with a pathological process and have putative diagnostic and/or prognostic utility. In migraine, clinical, radiological, and biochemical biomarkers might be helpful to improve diagnosis, get insight in pathophysiology, and facilitate tr...

journal_title：Headache

authors： De Vries B,Haan J,Frants RR,Van den Maagdenberg AM,Ferrari MD

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:To establish if criteria for the diagnosis of migraine change with age and to document the influence of age on the full spectrum of migraine features. Also to define the clinical spectrum and provide a prognostic profile of migraine stratified by age. BACKGROUND:Few studies have formally analyzed migraine ch...

journal_title：Headache

authors： Kelman L

更新日期：2006-07-01 00:00:00

abstract：:Two cases of baroreflex failure presented with tension-type/exertional headache. The usefulness of noninvasive physiological tests in diagnosing baroreflex failure and the role of baroreceptors in trigeminal nociception are discussed. ...

journal_title：Headache

authors： Khurana RK

更新日期：2006-07-01 00:00:00

abstract：:Observations including the long-recognized tendency of migraine to run in families, the high concordance rates for migraine in twins reared together or apart, and the association of specific mutations with a rare migraine form are consistent with a genetic contribution to the disorder. This paper summarizes major find...

journal_title：Headache

authors： Gardner KL

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:This study describes the pain characteristics of the acute migraine attack, including time of onset, time to peak, duration, intensity, quality, aggravation by activity, as well as recurrence frequency and time to recurrence, in a tertiary care practice. BACKGROUND:The literature documenting the characteris...

journal_title：Headache

authors： Kelman L

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The sequence and timing of taking migraine medications, whether prescription or over-the-counter, and the patient's response to their treatment, is unknown. OBJECTIVE:To describe the use of, response to, and satisfaction with acute medications for 1 migraine attack. METHODS:We performed a clinic-based surv...

journal_title：Headache

authors： Malik SN,Hopkins M,Young WB,Silberstein SD

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Mechanical compression of the trigeminal root by an artery is thought to cause trigeminal neuralgia. The 5-HT(1B/1D) receptor agonist may inhibit neurogenic inflammation and vasodilation near the irritated trigeminal root. OBJECTIVE:To examine the effectiveness of a 5-HT(1B/1D) receptor agonist, sumatriptan...

journal_title：Headache

authors： Kanai A,Saito M,Hoka S

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The objective of this study was to investigate the prevalence and sociodemographic characteristics of headaches among Turkish adolescents aged 12 to 17 years old in Bursa province of Turkey. METHODS:A multistep, stratified, cluster sampling method was used for subject selection. The estimated...

journal_title：Headache

authors： Karli N,Akiş N,Zarifoğlu M,Akgöz S,Irgil E,Ayvacioğlu U,Calişir N,Haran N,Akdoğan O

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To explore the effects of olmesartan on frequency and severity of migraine attacks in patients with comorbid hypertension and prehypertension. BACKGROUND:A randomized, double-blind, placebo-controlled, crossover study with a total of 60 patients has demonstrated the efficacy and safety of the angiotensin II ...

journal_title：Headache

authors： Charles JA,Jotkowitz S,Byrd LH

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and tolerability of sumatriptan nasal spray (NS) (5, 20 mg) versus placebo in the acute treatment of migraine in adolescent subjects. BACKGROUND:Currently, no triptan is approved in the United States for the treatment of migraine in adolescent subjects (12 to 17 years). In a previous ...

journal_title：Headache

authors： Winner P,Rothner AD,Wooten JD,Webster C,Ames M

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the prevalence, demographic, clinical features, and possible risk factors for hemodialysis headache (HDH). BACKGROUND:HDH has been recognized for many years, but the pathophysiology of this condition is not known. High arterial blood pressure, decreased serum osmolality,...

journal_title：Headache

authors： Goksel BK,Torun D,Karaca S,Karatas M,Tan M,Sezgin N,Benli S,Sezer S,Ozdemir N

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:To determine the association between the severity of premenstrual (PMS) symptoms and headache outcome measures during natural menstrual cycles and after medical oophorectomy. BACKGROUND:Premenstrual syndrome may occur in 64% of those with pure menstrual migraine and 33% of those with menstrually related mig...

journal_title：Headache

authors： Martin VT,Wernke S,Mandell K,Ramadan N,Kao L,Bean J,Liu J,Zoma W,Rebar R

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the sensitivity of the new International Classification of Headache Disorders-2nd edition (ICHD-II) criteria in the diagnosis of childhood migraine and to propose specific criteria for the diagnosis of childhood migraine. BACKGROUND:In 2004, ICHD-II was adopted by the International Headache Socie...

journal_title：Headache

authors： Hershey AD,Winner P,Kabbouche MA,Gladstein J,Yonker M,Lewis D,Pearlman E,Linder SL,Rothner AD,Powers SW

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To investigate the habituation response pattern of patients with migraine to a simple standard stressor and to a more complex performance-dependent (achievement) stressor in three peripheral systems (electrodermal, vasomotor, and cardiovascular). We hypothesized that the migraine patients would show abnormal ...

journal_title：Headache

authors： Huber D,Henrich G,Gündel H

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:To examine test-retest reliability of magnetic suppression of perceptual accuracy (MSPA) prior to its use as a marker of cortical excitability in a trial of migraine prophylactic agents. BACKGROUND:MSPA is a relatively novel avenue of research in headache, providing an opportunity to study cortical responsi...

journal_title：Headache

authors： Custers A,Mulleners WM,Chronicle EP

更新日期：2005-10-01 00:00:00

abstract：:Patients suffering from cervicogenic headache (CeH) are commonly treated with spinal manipulative therapy. We have analyzed the quality and the outcomes of published, randomized, controlled trials assessing the effectiveness of spinal manipulation in CeH. Among 121 relevant articles, only two met all the inclusion cri...

journal_title：Headache

authors： Fernández-de-Las-Peñas C,Alonso-Blanco C,Cuadrado ML,Pareja JA

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To address the need for a rigorous, direct comparison of prescription and over-the-counter (OTC) migraine drugs and to expand the database on early treatment of migraine. BACKGROUND:Most people who experience migraine use OTC medications to treat their symptoms, but no head-to-head clinical trials comparing ...

journal_title：Headache

authors： Goldstein J,Silberstein SD,Saper JR,Elkind AH,Smith TR,Gallagher RM,Battikha JP,Hoffman H,Baggish J

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between a serotonin (5-HT) transporter gene polymorphism and migraines in Koreans. BACKGROUND:The 5-HT metabolism is believed to play an important part in the pathophysiology of migraines, and a polymorphism of the serotonin transporter (5-HTT) promoter region might influence 5-HT...

journal_title：Headache

authors： Kim WK,Kim HS,Kim WJ,Lee KY,Park H,Kim CH,Kim SJ,Choi YC

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To examine circadian and menstrual patterns of migraine frequency in order to identify properties of the putative migraine generator. METHODS:Analysis of circadian and menstrual migraine attack frequency distributions, using between-interval differences as estimates, at each time point, of the derivative of ...

journal_title：Headache

authors： Fox AW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features of children with chronic daily headache (CDH) and examine the usefulness of the International Classification of Headache Disorders-II. BACKGROUND:Few data are available on chronic daily headache and analgesic overuse in children and adolescents and there are no specific crit...

journal_title：Headache

authors： Wiendels NJ,van der Geest MC,Neven AK,Ferrari MD,Laan LA

更新日期：2005-06-01 00:00:00

abstract：:We present a patient with treatment refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) who was found to have low levels of serum testosterone supporting the hypothalamic connection to this trigeminal autonomic cephalalgia. Clomiphene citrate therapy induce...

journal_title：Headache

authors： Rozen TD,Saper JR,Sheftell FD,Dodick DW

更新日期：2005-06-01 00:00:00

abstract：:The majority of research conducted on headache has utilized cross-sectional designs which preclude the examination of dynamic factors and principally rely on group-level effects. The present article describes the application of an individual-oriented process model using time-series analytical techniques. The blending ...

journal_title：Headache

authors： Houle TT,Remble TA,Houle TA

更新日期：2005-05-01 00:00:00

abstract：:Three decades of research has produced effective behavioral treatments for migraine and tension-type headache, yet the full fruition of this research has not been realized. Further development and dissemination of behavioral treatments is needed to impact the large numbers of those with headache who potentially could ...

journal_title：Headache

authors： Penzien DB,Rains JC,Lipchik GL,Nicholson RA,Lake AE 3rd,Hursey KG

更新日期：2005-05-01 00:00:00

abstract：:Topiramate is a neuromodulatory compound with stabilizing properties that was initially introduced for the management of partial seizures. Topiramate has been demonstrated to modify several receptor-gated and voltage-sensitive ion channels, including voltage-activated Na+ and Ca2+ channels and non-NMDA receptors. Thes...

journal_title：Headache

authors： White HS

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To investigate variation in headache occurrence and characteristics over 1 year. BACKGROUND:Headache is a common condition which can affect the work, home, and social lives of sufferers, yet surprisingly little is known about how headache changes over time. METHODS:Postal survey to a random general populati...

journal_title：Headache

authors： Boardman HF,Thomas E,Millson DS,Croft PR

更新日期：2005-04-01 00:00:00

abstract：:Ischemic colitis has not been reported in association with naratriptan therapy. We describe the occurrence of ischemic colitis in a patient who was treated with abortive doses of naratriptan for migraine and was also taking long-term oral contraceptives. Concurrent use of naratriptan and oral contraceptives should pro...

journal_title：Headache

authors： Charles JA,Pullicino PM,Stoopack PM,Shroff Y

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of venlafaxine in the prophylaxis of migraine. BACKGROUND:The efficacy of venlafaxine, which is selectively effective on the serotonergic and noradrenergic mechanisms, on various headaches and chronic pain syndromes has been demonstrated. To our knowledge, this is the firs...

journal_title：Headache

authors： Ozyalcin SN,Talu GK,Kiziltan E,Yucel B,Ertas M,Disci R

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:The aim of our study is to determine the prevalence of migraine in Provincial Center of Edirne. METHODS:A systematic random sample of 386 inhabitants over 14 years old were interviewed face to face. Diagnosis of migraine was based on the International Headache Society (IHS) classification. RESULTS:Migraine...

journal_title：Headache

authors： Celik Y,Ekuklu G,Tokuç B,Utku U

更新日期：2005-01-01 00:00:00

abstract：:We report the case of a man with episodic cluster headache who suffered from severe obstructive sleep apnea (OSA) as well as periodic limb movements during sleep (PLMS). His attacks of headache occurred primarily during sleep being timely to REM sleep as 90 to 120 minutes interval. OSAs were more frequent and prolonge...

journal_title：Headache

authors： Pelin Z,Bozluolcay M

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:A recent study conducted in triptan-naive migraine patients showed that tolerability was the second most important attribute of an acute treatment. However, the proportion of patients reporting side effects after any acute treatment may vary with regard to the method of assessment. OBJECTIVES:To contrast tw...

journal_title：Headache

authors： Sheftell FD,Feleppa M,Tepper SJ,Rapoport AM,Ciannella L,Bigal ME

更新日期：2004-11-01 00:00:00

abstract：:Unilateral hairlike discoloration of the tongue is described in a patient with ipsilateral mandibular division trigeminal neuralgia. This unusual physical sign coincided with the patient's painful trigger zone and was attributed to hypertrophy of keratinized filiform papillae, where guarded avoidance of mechanical sti...

journal_title：Headache

authors： Cheshire WP Jr

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To determine the brain structures involved in mediating the pain of hemicrania continua using positron emission tomography. BACKGROUND:Hemicrania continua is a strictly unilateral, continuous headache of moderate intensity, with superimposed exacerbations of severe intensity that are accompanied by trigemina...

journal_title：Headache

authors： Matharu MS,Cohen AS,McGonigle DJ,Ward N,Frackowiak RS,Goadsby PJ

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To determine (1) the clinical course of a sample of chronic migraine patients with drug overuse 6 and 12 months following in-patient treatment and (2) whether functional impairment, assessed by the Migraine Disability Assessment (MIDAS) questionnaire, improved upon treatment. BACKGROUND:Patients with chronic...

journal_title：Headache

authors： Grazzi L,Andrasik F,D'Amico D,Usai S,Kass S,Bussone G

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To examine the direct medical costs associated with migraine, when diagnosed alone and in conjunction with anxiety and/or depression in adults and children. BACKGROUND:Migraine is a common disorder that can often be accompanied by comorbid anxiety and/or depression. Given the prevalence of migraine and the l...

journal_title：Headache

authors： Pesa J,Lage MJ

更新日期：2004-06-01 00:00:00

abstract：:Traditionally, episodic primary headache disorders are characterized by a return of preheadache (normal) neurologic function between episodes of headache. In contrast, patients with chronic headache often do not return to normal neurologic function between headache attacks. This article proposes that the evolution fro...

journal_title：Headache

authors： Cady RK,Schreiber CP,Farmer KU

更新日期：2004-05-01 00:00:00

abstract：:Triptans are not widely used in clinical practice despite their well-established efficacy, endorsement by the US Headache Consortium, and the demonstrable need to employ effective intervention to reduce migraine-associated disability. Although the relatively restricted use of triptans may be attributed to several fact...

journal_title：Headache

authors： Dodick DW,Martin VT,Smith T,Silberstein S

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:A beneficial prophylactic effect from eletriptan 40 mg given to a single patient with cluster headache was observed. OBJECTIVE:To further evaluate the efficacy of eletriptan in the short-term prophylaxis of cluster headache. METHODS:We treated 18 patients; mean age, 40.5 years (standard deviation [SD], 9.9...

journal_title：Headache

authors： Zebenholzer K,Wöber C,Vigl M,Wessely P

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Migraine occurs in 3% to 5% of young children and up to 18% of adolescents. Management requires a tailored regimen of pharmacological and behavioral measures that consider the headache burden and disability. Patients with frequent or disabling attacks (or both) may warrant preventive agents. OBJECTIVE:To in...

journal_title：Headache

authors： Lewis DW,Diamond S,Scott D,Jones V

更新日期：2004-03-01 00:00:00